DHEA in 2025: What You Need to Know About This Foundational Hormone

Jessica Boggs • May 12, 2025

How Supporting This Vital Hormone Can Restore Balance and Vitality at Any Age

Balancing Energy, Mood, Metabolism, and Hormones with Precision


As we age, our bodies experience a natural decline in several hormones that are essential for health and vitality—including DHEA (dehydroepiandrosterone). This critical adrenal hormone is a precursor to both estrogen and testosterone and plays a pivotal role in regulating energy, mood, metabolism, cognitive clarity, and sexual health.


At JaeNix Med Spa & Wellness Lounge, we assess DHEA as part of a comprehensive hormone panel to uncover imbalances that may be silently affecting your well-being. Here’s what you need to know about this underrated hormone in 2025.


โ“ What Is DHEA?

DHEA is a steroid hormone primarily produced by your adrenal glands and, to a lesser extent, by the gonads and brain. It’s the most abundant steroid hormone in the human body and serves as a precursor to androgens and estrogens, the hormones responsible for reproductive and metabolic health.


๐Ÿงฌ DHEA production peaks in your 20s and then declines gradually—dropping by more than 50% by age 50 and up to 80–90% by age 70.


๐Ÿ”ฌ Why DHEA Matters in 2025

Modern research continues to reinforce DHEA’s relevance as more than just a “youth hormone.” In today’s fast-paced, high-stress world, adrenal dysregulation, inflammation, and hormone imbalances are on the rise. Supporting optimal DHEA levels can help:

Protect against age-related decline

Restore mental clarity and motivation

Boost sexual function and libido

Improve metabolic health and insulin sensitivity

Reduce visceral fat and inflammation

Strengthen immune resilience

Support bone density and joint health


โš ๏ธ Symptoms of Low DHEA

If your DHEA levels are declining, you may notice:

Fatigue or low stamina

Brain fog or memory lapses

Depressed mood or anxiety

Low libido

Erectile dysfunction or vaginal dryness

Muscle weakness or bone loss

Increased belly fat or insulin resistance

Salt cravings or dizziness (linked to adrenal fatigue)

DHEA levels are often missed in standard lab workups, which is why we test DHEA-Sulfate (DHEA-S) in all hormone optimization panels.


โœ… Benefits of DHEA Supplementation (When Clinically Indicated)


When prescribed by a trained provider, DHEA supplementation has shown to:

โœ” Improve mood and reduce depression in midlife and older adults
โœ” Boost free testosterone and estradiol production
โœ” Improve sexual satisfaction and arousal
โœ” Support bone mineral density in postmenopausal women
โœ” Reduce inflammatory cytokines and oxidative stress
โœ” Enhance cognitive performance and memory
โœ” Improve insulin sensitivity and reduce blood sugar spikes
โœ” Help reverse early signs of adrenal insufficiency or burnout


๐Ÿงช Research in 2024 continues to support DHEA’s role as a longevity-supportive hormone—especially when paired with personalized hormone replacement therapy and targeted nutraceuticals.


๐Ÿงพ DHEA Testing & Treatment at JaeNix Med Spa & Wellness Lounge


We measure DHEA-Sulfate as part of your comprehensive lab panel and evaluate it alongside cortisol, estradiol, testosterone, and thyroid markers to get a full picture of your hormonal health.


If supplementation is needed, we provide:

Sustained-release DHEA capsules (typically 5–50 mg daily)

Compounded DHEA/Progesterone or DHEA/Pregnenolone blends

Adrenal support stacks combining adaptogens, methylation cofactors, and micronutrients


๐Ÿ’ก DHEA is not a “one-size-fits-all” hormone. Over-supplementation can lead to acne, hair loss, irritability, or unwanted androgenic effects—especially in women. That’s why we individualize your dosing based on labs, symptoms, and overall goals.


๐Ÿฉบ Start Your Hormone Optimization Journey Today


If you suspect your hormones are off—or you’re dealing with fatigue, brain fog, or low libido—DHEA may be part of the picture.

๐Ÿ“ Visit us at JaeNix Med Spa & Wellness Lounge |  Plano, TX
๐Ÿ“ž Call: 214-890-6180
๐Ÿ’ป Schedule: www.jaenixwellness.com


Let us help you take back your energy, vitality, and clarity—one hormone at a time.

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